The drive worked with both Macs and Windows computers in my testing. Again, all you need to do is plug it into a computer using the included (or any standard) Mini-USB cable and you are all set. There's virtually no setting up required with the Samsung SE-218BB. Its burning speeds are actually plenty fast for most situations and are those supported by most blank media on the market. For this reason, there's no need for the drive to support USB 3.0, since USB 2.0's speed caps at about 60MBps, much faster than the drive's burning and reading speeds. The Samsung SE-218BB can burn dual-layer DVDs at 6x (about 8MBps) and CDs at 24x (about 3.5MBps).
This helps make it more portable and means that you can use the drive with any standard Mini-USB cable, in case you misplace the one that came with it. Unlike other portable burners I've seen that require two USB ports to draw enough power - and come with a Y-shaped USB cable to accommodate that - the Samsung SE-218BB just needs the one Mini-USB port to work.